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Surfactant Protein B Cross Reactive with Mouse, Bovine and Pig Sp-B 抗体

适用: 人 IA, IHC (fro), IHC (p), WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2192204
发货至: 中国
  • 抗原
    Surfactant Protein B Cross Reactive with Mouse, Bovine and Pig Sp-B
    适用
    宿主
    克隆类型
    多克隆
    应用范围
    Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    过滤
    0.2 μm filtered
  • 应用备注
    For immunohistology and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • Nogee, Wert, Proffit, Hull, Whitsett: "Allelic heterogeneity in hereditary surfactant protein B (SP-B) deficiency." in: American journal of respiratory and critical care medicine, Vol. 161, Issue 3 Pt 1, pp. 973-81, (2000) (PubMed).

    Clark, Wert, Bachurski, Stahlman, Stripp, Weaver, Whitsett: "Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 17, pp. 7794-8, (1995) (PubMed).

    Gregory, Longmore, Moxley, Whitsett, Reed, Fowler, Hudson, Maunder, Crim, Hyers: "Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome." in: The Journal of clinical investigation, Vol. 88, Issue 6, pp. 1976-81, (1992) (PubMed).

    Weaver, Sarin, Sawtell, Hull, Whitsett: "Identification of surfactant proteolipid SP-B in human surfactant and fetal lung." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 65, Issue 2, pp. 982-7, (1988) (PubMed).

    Whitsett, Hull, Ohning, Ross, Weaver: "Immunologic identification of a pulmonary surfactant-associated protein of molecular weight = 6000 daltons." in: Pediatric research, Vol. 20, Issue 8, pp. 744-9, (1986) (PubMed).

  • 抗原
    Surfactant Protein B Cross Reactive with Mouse, Bovine and Pig Sp-B
    背景
    The polyclonal antibody recognizes the human surfactant protein B (SP-B). There are four surfactant- specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-B is synthesized by the alveolar type II epithelial cells as a 40-42 kD precursor that is subsequently proteolytically processed to 7.8-8 kD. SP-B enhances the spreading and
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