(3 references)-
- 抗原 See all Lactoferrin (LTF) 抗体
- Lactoferrin (LTF) (Lactotransferrin (LTF))
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适用
- 人
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宿主
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牛
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克隆类型
- 多克隆
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标记
- This Lactoferrin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunoassay (IA)
- 过滤
- 0.2 μm filtered
- Top Product
- Discover our top product LTF Primary Antibody
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anti-Lactotransferrin (LTF) antibody
LTF 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 25-352) antibodyLTF 适用: 山羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) antibodyLTF 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB22673 unconjugated
anti-Lactotransferrin (LTF) (AA 219-248) antibodyLTF 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB11921 unconjugated
anti-Lactotransferrin (LTF) (AA 500-710) antibodyLTF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 63-193) antibodyLTF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 28-351) antibodyLTF 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) antibodyLTF 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) (AA 25-352) antibodyLTF 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lactotransferrin (LTF) antibodyLTF 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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: "Analytical cation-exchange chromatography to assess the identity, purity, and N-terminal integrity of human lactoferrin." in: Analytical biochemistry, Vol. 309, Issue 1, pp. 60-6, (2002) (PubMed).
: "Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria." in: Infection and immunity, Vol. 69, Issue 3, pp. 1469-76, (2001) (PubMed).
: "Characterization of recombinant human lactoferrin secreted in milk of transgenic mice." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8802-7, (1997) (PubMed).
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: "Analytical cation-exchange chromatography to assess the identity, purity, and N-terminal integrity of human lactoferrin." in: Analytical biochemistry, Vol. 309, Issue 1, pp. 60-6, (2002) (PubMed).
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- 抗原
- Lactoferrin (LTF) (Lactotransferrin (LTF))
- 别名
- Lactoferrin (LTF 产品)
- 别名
- LTF antibody, GIG12 antibody, HLF2 antibody, LF antibody, Lf antibody, Csp82 antibody, MMS10R antibody, Ms10r antibody, PLF antibody, TFEW antibody, conalbumin antibody, lactotransferrin antibody, transferrin antibody, transferrin (ovotransferrin) antibody, LTF antibody, CpipJ_CPIJ000114 antibody, TF antibody, Ltf antibody
- 背景
- Human lactoferrin (LF) is an 80 kDa glycoprotein which was first isolated from human milk. It plays an important part in the immune system and helps to fight infections. Lactoferrin promotes the health of the gastro-intestinal system by improving the intestinal microbial balance. In addition, LF can be found in epithelia and most body fluids and secretions. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration also represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation. Lactoferrin strongly binds to iron and this iron binding property is considered to be an important antimicrobial. Human lactoferrin binds to bacterial products through its highly positively charged N- terminus, it kills various bacteria, most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Cleavage by pepsin of lactoferrin leads to the release of lactoferricin H. This 47 amino acid peptide has more antimicrobial activity than its precursor and it can inhibit the classical but not the alternative complement pathway. Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.
- 途径
- Transition Metal Ion Homeostasis
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