Lactoferrin, C-Lobe 抗体
This 小鼠 单克隆 antibody specifically detects Lactoferrin, C-Lobe in IA 和 WB. It exhibits reactivity toward Cow.It has been mentioned in 1 publication
(1 reference)
产品编号 ABIN2192137
发货至:
中国
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Quick Overview for Lactoferrin, C-Lobe 抗体 (ABIN2192137)
抗原
Lactoferrin, C-Lobe
适用
Cow
宿主
小鼠
克隆类型
单克隆
应用范围
Immunoassay (IA), Western Blotting (WB)
克隆位点
A-bC-lobe
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过滤
- 0.2 μm filtered
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应用备注
- For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
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限制
- 仅限研究用
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缓冲液
- PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
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有效期
- 12 months
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: "Structural and immunochemical studies on bovine lactoferrin fragments." in: Advances in experimental medicine and biology, Vol. 443, pp. 41-8, (1998) (PubMed).
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- Lactoferrin, C-Lobe
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背景
- Monoclonal antibody a-bC-lobe, anti bovine Lactoferrin (Lf) is highly specific for bovine Lactoferrin. This protein is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. It shows multifunctional properties of which the bacteriostatic and bactericidal effects are the best known. The molecule is constructed with a N-terminal half molecule (N-lobe) and a C- terminal half molecule (C-lobe), each of which is composed of two domains. The biologically important functions have been found mainly in the N-lobe. The lactoferrin determinants responsible for binding to Ca2+-dependent receptor on hepatocytes are present within the C-lobe. The monoclonal antibody a-bC- lobe shows strong reactivities with both native and denatured forms of bovine lactoferrin and C-lobe. The 'WNIPMGL' sequence (467-473 of bovine lactoferrin) is the antigenic determinant or epitopic site of the anti C-lobe antibody a-bC-lobe. The antibody shows weak reactivity with human lactoferrin and korean goat lactoferrin, slight cross reactivity is seen with bovine transferrin, whereas no cross reactivity is seen with human transferrin and chicken ovotransferrin.
抗原
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