beta 2 Adrenergic Receptor 抗体
(2 references)-
- 抗原 See all beta 2 Adrenergic Receptor (ADRB2) 抗体
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This beta 2 Adrenergic Receptor antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func), Immunoassay (IA)
- 交叉反应 （详细）
- Cross reactivity: Rat : Yes, Guinea Pig : Yes
- 过滤
- 0.2 μm filtered
- 克隆位点
- 6H8
- 亚型
- IgG1
- Top Product
- Discover our top product ADRB2 Primary Antibody
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anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 201-300) antibody
ADRB2 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (pSer346) antibodyADRB2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 302-413) antibodyADRB2 适用: 人, 大鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G3B5 unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyADRB2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 1-413) antibodyADRB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 1-413) antibodyADRB2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyVerified ADRB2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyADRB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (pSer346) antibodyADRB2 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) antibodyADRB2 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 4C11 unconjugated Recombinant Antibody
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- 应用备注
- For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting. Positive Human epidermoid carcinoma cell A431 line control
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.1 % bovine serum albumin
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
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: "From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-beta(2)-adrenoceptor antibody behave as antagonists." in: Molecular pharmacology, Vol. 58, Issue 2, pp. 373-9, (2000) (PubMed).
: "An agonist-like monoclonal antibody against the human beta2-adrenoceptor." in: European journal of pharmacology, Vol. 348, Issue 1, pp. 123-33, (1998) (PubMed).
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: "From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-beta(2)-adrenoceptor antibody behave as antagonists." in: Molecular pharmacology, Vol. 58, Issue 2, pp. 373-9, (2000) (PubMed).
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- 抗原
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
- 别名
- Beta2-Adrenoceptor (ADRB2 产品)
- 别名
- zgc:162188 antibody, adrb2 antibody, Adrb-2 antibody, Badm antibody, Gpcr7 antibody, ADRB2R antibody, ADRBR antibody, B2AR antibody, BAR antibody, BETA2AR antibody, adrenoceptor beta 2 antibody, adrenoceptor beta 2, surface b antibody, beta2-adrenergic receptor antibody, adrenergic receptor, beta 2 antibody, ADRB2 antibody, adrb2b antibody, LOC100136153 antibody, Adrb2 antibody
- 背景
- The monoclonal antibody 6H8 recognizes human beta2-adrenoceptor. The b -adrenoceptors can be divided into b1, b2, b3 and b4-adrenoceptors defined in terms of agonist potencies, b2-adrenoceptors displayed a higher selectivity for nor-adrenaline than for adrenaline. B2-receptors are mainly postsynaptic and are located on a number of tissues including blood vessels, bronchi, GIT, skeletal muscle, liver and mast cell. Activation results in vasodilatation, bronchodilation, relaxation of the GIT, glycogenolysis in the liver, tremor in skeletal muscle and inhibition of histamine release from mast cells. Transduction is via G-proteins coupled to the intracellular second messenger adenylate cyclase. B- receptors are positively coupled to adenylate cyclase via activation of Gs G-protein, however activation of the b2-adrenoceptors results in stimulation and inhibition of adenylate cyclase. The b2- receptor selective agonists are widely used in the treatment of asthma and other related bronchospastic conditions. They are commonly used in the treatment of angina pectoris, cardiac arrhythmia and for the long-term treatment of patients who survive myocardial infarction. B-receptor antagonists have also been used as anti-hypertensive for a number of years. Beta -blockers have also proven useful in the treatment of conditions such as migraine, anxiety disorders, hyperthyroidism, alcohol withdrawal and when applied topically are useful in the treatment of glaucoma and ocular hypertension. Immunogen Free peptide Beta2-H19C
- 途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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