PMP22 抗体
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- 抗原 See all PMP22 抗体
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PMP22 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoassay (IA)
- 过滤
- 0.2 μm filtered
- 克隆位点
- CF1
- Top Product
- Discover our top product PMP22 Primary Antibody
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anti-Peripheral Myelin Protein 22 (PMP22) (AA 101-160) antibody
PMP22 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (C-Term) antibodyPMP22 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 1-64) antibodyPMP22 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 120-133), (Extracellular Domain) antibodyPMP22 适用: 人, 猴, 灵长类 IHC (p) 宿主: 小鼠 Monoclonal Hu1 unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (C-Term) antibodyPMP22 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 31-133) antibodyPMP22 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 31-133) antibodyPMP22 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 32-64) antibodyPMP22 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) antibodyPMP22 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (C-Term) antibodyPMP22 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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- 抗原
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
- 别名
- Peripheral Myelin Protein 22 (PMP22 产品)
- 别名
- CMT1A antibody, CMT1E antibody, DSS antibody, GAS-3 antibody, HMSNIA antibody, HNPP antibody, Sp110 antibody, 22kDa antibody, Gas-3 antibody, Tr antibody, trembler antibody, pmp22 antibody, wu:fa04d03 antibody, wu:fa08d03 antibody, MGC80653 antibody, PMP22 antibody, MGC69407 antibody, id:ibd2630 antibody, wu:fb81f09 antibody, zgc:136919 antibody, peripheral myelin protein 22 antibody, peripheral myelin protein 22a antibody, peripheral myelin protein 22 S homeolog antibody, peripheral myelin protein 22b antibody, PMP22 antibody, Pmp22 antibody, pmp22a antibody, pmp22.S antibody, pmp22 antibody, pmp22b antibody
- 背景
- The monoclonal antibody CF1 recognizes human peripheral myelin protein 22 (PMP22). PMP22 is a 160 amino acid glycoprotein and contains four hydrophobic domains, presumably transmembrane regions. It is the second most abundant protein in the mammalian nervous system, but is, at least in rodents, also found in other tissues, including the liver and gut. Myelin protein zero (P0) is the most abundant protein in mammalian peripheral nerve myelin. An interaction between P0 and PMP22 has been detected in compact myelin. Defects in PMP22 have been related to Charcot-Marie-Tooth disease (CMT) and inflammatory demyelinating neuropathy (IDP). Immunization with PMP22 induces experimental auto-immune neuritis without central nervous inflammation. Therefore, PMP22 is considered as candidate auto-antigen in inflammatory diseases of the peripheral nervous system, including both acute and chronic inflammatory demyelinating polyradiculoneuropathy. Monoclonal antibody CF1 is crossreactive with Rhesus monkey PMP22. Aliases Growth arrest-specific protein 3, Gas-3 Immunogen Peptide corresponding to amino acids 121-133 in the second extracellular domain of human PMP2 with an extra N-terminal cysteine residue (CRHPEWHLNSDYSYG)
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