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Lipocalin 2 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-Lipocalin 2 antibody is suitable to detect Lipocalin 2 in samples from 人. It has been validated for IF 和 IA.
产品编号 ABIN2192048
发货至: 中国
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Quick Overview for Lipocalin 2 抗体 (ABIN2192048)

抗原

See all Lipocalin 2 (LCN2) 抗体
Lipocalin 2 (LCN2)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Lipocalin 2 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunoassay (IA)

克隆位点

697
  • 过滤

    0.2 μm filtered
  • 应用备注

    For immunofluorescence dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

    限制

    仅限研究用
  • 缓冲液

    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

    有效期

    12 months
  • Metso, Venge, Haahtela, Peterson, Sevéus: "Cell specific markers for eosinophils and neutrophils in sputum and bronchoalveolar lavage fluid of patients with respiratory conditions and healthy subjects." in: Thorax, Vol. 57, Issue 5, pp. 449-51, (2002) (PubMed).

  • 抗原

    Lipocalin 2 (LCN2)

    背景

    The monoclonal antibody 697 reacts with human neutrophil lipocalin (HNL), also known as human nGAL (25 kDa). Lipocalins are a widespread family of small, robust proteins that typically transport or store biological compounds which are either of low solubility or are chemically sensitive, including vitamins, steroids, odorants and metabolic products. The members of this lipocalins share a high similarity in their tertiary structures in spite of a low degree in amino-acid sequence identity: three highly conserved sequence motifs form a funnel-like beta barrel which encloses a hydrophobic pocket for the internal ligand binding. The human neutrophil lipocalin (HNL) is produced by neutrophil leukocytes and stored in intracellular specific granules. Neutrophil lipocalin is covalently linked to gelatinase B (MMP-9) and proMMP is stored in three forms: the monomeric form (92 kDa), the homodimer (220 kDa) and a heterodimer (125 kDa). During inflammation and neoplastic transformation the human neutrophil lipocalin (HNL) is produced in neutrophils and in epithelial cells. Furthermore neutrophil lipocalin is a superior means to distinguish acute bacterial and viral infections as well as it enables the determination of the neutrophil activation level.

    途径

    Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
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