JAM3 抗体
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北京 101111
Quick Overview for JAM3 抗体 (ABIN2191806)
抗原
See all JAM3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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过滤
- 0.2 μm filtered
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anti-Junctional Adhesion Molecule 3 (JAM3) (AA 119-235) antibody
JAM3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Junctional Adhesion Molecule 3 (JAM3) (AA 31-130) antibodyJAM3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (fro), IF (cc), IF (p), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Junctional Adhesion Molecule 3 (JAM3) (AA 1-310) antibodyJAM3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Junctional Adhesion Molecule 3 (JAM3) antibodyJAM3 适用: 人, 小鼠 FACS, IF, IHC (fro) 宿主: 大鼠 Monoclonal CRAM-18 F26 unconjugated
anti-Junctional Adhesion Molecule 3 (JAM3) (AA 82-180) antibodyJAM3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Junctional Adhesion Molecule 3 (JAM3) (AA 36-85) antibodyJAM3 适用: 人, 小鼠, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Junctional Adhesion Molecule 3 (JAM3) (N-Term) antibodyJAM3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Junctional Adhesion Molecule 3 (JAM3) (AA 30-241) antibodyJAM3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- For immunohistology and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
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限制
- 仅限研究用
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缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
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有效期
- 12 months
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: "Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration." in: Blood, Vol. 100, Issue 7, pp. 2479-86, (2002) (PubMed).
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: "Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration." in: Blood, Vol. 100, Issue 7, pp. 2479-86, (2002) (PubMed).
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- JAM3 (Junctional Adhesion Molecule 3 (JAM3))
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别名
- Junctional Adhesion Molecule-C
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背景
- Junctional adhesion molecule-C (JAM-C) also known as JAM-2 is a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the vascular endothelium, in particular of high endothelial venules (HEV). In adult murine tissue JAM-C expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney. Monoclonal antibody CRAM-19 H36 also reacts with human JAM-C. In humans, JAM-C expression is not restricted to endothelial cells, but is also expressed on human lymphocytes.
抗原
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