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F11R 抗体

This anti-F11R antibody is a 大鼠 单克隆 antibody detecting F11R in WB, FACS, IP 和 IF. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2191795
发货至: 中国

Quick Overview for F11R 抗体 (ABIN2191795)

抗原

See all F11R 抗体
F11R (F11 Receptor (F11R))

适用

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小鼠

宿主

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  • 1
  • 1
大鼠

克隆类型

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  • 3
单克隆

标记

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This F11R antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

BV12
  • 交叉反应 (详细)

    Cross reactivity: Human : No

    过滤

    0.2 μm filtered

    亚型

    IgG2a
  • 应用备注

    For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

    限制

    仅限研究用
  • 缓冲液

    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Product should be stored at 4 °C Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Martinez-Estrada, Manzi, Tonetti, Dejana, Bazzoni: "Opposite effects of tumor necrosis factor and soluble fibronectin on junctional adhesion molecule-A in endothelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 288, Issue 6, pp. L1081-8, (2005) (PubMed).

  • 抗原

    F11R (F11 Receptor (F11R))

    别名

    Junctional Adhesion Molecule-A

    背景

    The monoclonal antibody BV12 recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R), is a cell adhesion molecule (CAM). JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM- 3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading. Aliases JAM-1, platelet F11-Receptor, F11R

    途径

    Cell-Cell Junction Organization
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