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TSPAN12 抗体 (PE)

This anti-TSPAN12 antibody is a 兔 多克隆 antibody detecting TSPAN12 in FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN2179842
发货至: 中国

Quick Overview for TSPAN12 抗体 (PE) (ABIN2179842)

抗原

See all TSPAN12 抗体
TSPAN12 (Tetraspanin 12 (TSPAN12))

适用

  • 39
  • 23
  • 8
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
人, 大鼠, 小鼠

宿主

  • 39

克隆类型

  • 39
多克隆

标记

  • 17
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TSPAN12 antibody is conjugated to PE

应用范围

  • 20
  • 18
  • 13
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  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TSPAN12

    亚型

    IgG
  • 应用备注

    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4 °C for 12 months.
  • 抗原

    TSPAN12 (Tetraspanin 12 (TSPAN12))

    别名

    Tspan12

    背景

    TSPAN12 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. It is a regulator of cell surface receptor signal transduction and plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. It acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. It also acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. It activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP) and activates MMP14/MT1-MMP-dependent cleavage activity.
    Synonyms: TSPAN 12, NET 2, NET2, Tetraspan NET 2, Tetraspanin 12, Tetraspanin12, TM4SF12, Transmembrane 4 superfamily member 12, TSN12_HUMAN.

    基因ID

    23554
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