Surface Layer Protein (AA 301-400) 抗体 (AbBy Fluor® 647)
Quick Overview for Surface Layer Protein (AA 301-400) 抗体 (AbBy Fluor® 647) (ABIN2179504)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- Bacteria
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交叉反应 （详细）
- L.acidophilus, L.crispatus, L.helveticus, L.amylovorus, L.gallinarum
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from L, acidophilus S-layer protein
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Surface Layer Protein
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背景
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Synonyms: S-layer, Surface layer, surface layer protein, Slp, SLAP_LACAC, S-layer protein, slpA, sl pH , Lactobacillus surface layer protein,
Background: One of the most fascinating cell envelope structures in prokaryotic organisms is two-dimensional arrays of protein or glycoprotein subunits, termed S-layers (Surface Layers). They are composed of numerous identical subunits forming a symmetric, porous, lattice-like layer that completely covers the cell surface. The subunits are held together and attached to cell wall carbohydrates by non-covalent interactions, and they spontaneously reassemble in vitro by an entropy-driven process. In lactobacilli, S-layer proteins have been detected on many but not all species. Lactobacillus S-layer proteins differ from those of other bacteria in their smaller size and high predicted pI. The positive charge in Lactobacillus S-layer proteins is concentrated in the more conserved cell wall binding domain, which can be either N- or C-terminal depending on the species. The more variable domain is responsible for the self-assembly of the monomers to a periodic structure. The biological functions of Lactobacillus S-layer proteins are poorly understood, but in some species S-layer proteins mediate bacterial adherence to host cells or extracellular matrix proteins or have protective or enzymatic functions. Lactobacillus S-layer proteins show potential for use as antigen carriers in live oral vaccine design because of their adhesive and immunomodulatory properties and the general non-pathogenicity of the species.
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基因ID
- 3252774
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UniProt
- P35829
抗原
-
