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PCDHB6 抗体 (AA 21-120) (Cy7)

This anti-PCDHB6 antibody is a 兔 多克隆 antibody detecting PCDHB6 in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN2178289
发货至: 中国

Quick Overview for PCDHB6 抗体 (AA 21-120) (Cy7) (ABIN2178289)

抗原

PCDHB6 (Protocadherin beta 6 (PCDHB6))

适用

宿主

  • 16
  • 3

克隆类型

  • 17
  • 2
多克隆

标记

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PCDHB6 antibody is conjugated to Cy7

应用范围

  • 12
  • 12
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 1
    • 1
    • 1
    AA 21-120

    预测反应

    Human,Mouse,Rat,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PCDHB6

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PCDHB6 (Protocadherin beta 6 (PCDHB6))

    别名

    Pcdhb6

    背景

    Synonyms: PCDH beta6,,PCDH beta 6, PCDHB 6, Protocadherin beta 6.

    Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.

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