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OXSR1 抗体 (PE)

The PE-conjugated 兔 多克隆 anti-OXSR1 antibody (ABIN2178111) specifically detects OXSR1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2178111
发货至: 中国
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Quick Overview for OXSR1 抗体 (PE) (ABIN2178111)

抗原

See all OXSR1 抗体
OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This OXSR1 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human OXSR1.

    亚型

    IgG
  • 应用备注

    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4 °C for 12 months.
  • 抗原

    OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

    别名

    Oxsr1

    背景

    OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
    Synonyms: KIAA1101, OSR 1, OSR1, Oxidative stress responsive 1, Oxidative stress responsive 1 protein, OXSR 1, Serine/threonine protein kinase OSR1.

    基因ID

    9943

    途径

    Tube Formation
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