Transferrin Receptor 抗体
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- 抗原 See all Transferrin Receptor (TFRC) 抗体
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Transferrin Receptor antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- Recognizes mouse CD71, a 95kD cell surface protein that is otherwise known as transferrin receptor. CD71 is a major iron-binding protein, which plays a key role in the transport of iron into cells that require it. In mice, CD71 is widely expressed on a variety of cells, including Sertoli cells and cells which form the blood brain barrier (BBB) in the central nervous system. Recognizes native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the mouse.
- 纯化方法
- Protein G purified
- 内毒素水平
- Low Endotoxin
- 免疫原
- Mouse transformed endothelioma cell line t. end1.
- 克隆位点
- 8D3
- 亚型
- IgG2a
- Top Product
- Discover our top product TFRC Primary Antibody
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- 应用备注
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Approved: Flo (1:100 - 1:200), Func, IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 Method sheets are available on request. - 说明
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Target Species of Antibody: Mouse
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4.
- 注意事项
- Aliquot to Avoid freeze/thaw cycles. Store undiluted.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot to avoid freeze-thaw cycles. Store undiluted.
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- 抗原
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- 别名
- CD71 / Transferrin Receptor (TFRC 产品)
- 背景
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Name/Gene ID: TFRC
Subfamily: Metallopeptidase M28B
Family: Protease
Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1 - 基因ID
- 7037
- 途径
- Transition Metal Ion Homeostasis
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