LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) 抗体 (Cy7)
Quick Overview for LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) 抗体 (Cy7) (ABIN2177322)
抗原
See all LIM Domain Kinase 1/2 (LIMK1/2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr505
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
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亚型
- IgG
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anti-LIM Domain Kinase 1/2 (LIMK1/2) (pThr505), (pThr508) antibody
LIMK1/2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- LIM Domain Kinase 1/2 (LIMK1/2)
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别名
- LIMK1LIMK2
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背景
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Synonyms: LIMK1Thr508, EC 2.7.11.1, LIM domain kinase 1, LIM mot-containing protein kinase, LIMK, LIMK-1, LIMK2, LIMK-2, LIM domain kinase 2, LIMK1_HUMAN.
Background: LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development, it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
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基因ID
- 3984
抗原
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