LCMV Protein Z (AA 21-80) 抗体 (FITC)
Quick Overview for LCMV Protein Z (AA 21-80) 抗体 (FITC) (ABIN2177294)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-80
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交叉反应
- Virus
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交叉反应 （详细）
- Armstrong Strain LCMV
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产品特性
- Antibody is specific for: Armstrong Strain LCMV
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from LCMV Protein Z
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- LCMV Protein Z
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物质类
- Viral Protein
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背景
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Synonyms: Lymphocytic choriomeningitis virus.RING finger protein Z, Protein Z, Zinc-binding protein, Z_LYCVA.
Background: Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L (By similarity). Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. Also selectively represses protein production by associating with host eIF4E
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UniProt
- P18541
抗原
-
