IL12B 抗体 (AA 201-300)
(1 reference)Quick Overview for IL12B 抗体 (AA 201-300) (ABIN2176964)
抗原
See all IL12B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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亚型
- IgG
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anti-Interleukin 12 beta (IL12B) (AA 30-320) antibody
IL12B 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-327) antibodyIL12B 适用: 绵羊 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-328) antibodyIL12B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 229-328) antibodyIL12B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Interleukin 12 beta (IL12B) (AA 35-302) antibodyIL12B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) antibodyIL12B 适用: 人, Pig ELISA, IHC (fro) 宿主: 小鼠 Monoclonal I-1A4 unconjugated
anti-Interleukin 12 beta (IL12B) (C-Term) antibodyIL12B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-250) antibodyIL12B 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 4332-9, (2015) (PubMed).
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: "CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 4332-9, (2015) (PubMed).
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- IL12B (Interleukin 12 beta (IL12B))
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别名
- IL-12 beta
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背景
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Synonyms: CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL-12B, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, NK cell stimulatory factor chain 2, IL12B
Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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基因ID
- 3593
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UniProt
- P29460
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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