HLTF 抗体 (PE)
Quick Overview for HLTF 抗体 (PE) (ABIN2175888)
抗原
See all HLTF 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HLTF.
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亚型
- IgG
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应用备注
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FCM: (1:20-100)
Optimal working dilution should be determined by the investigator. -
说明
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Exitation/Emission: 480,565nm/578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4 °C for 12 months.
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- HLTF (Helicase-Like Transcription Factor (HLTF))
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别名
- Hltf
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背景
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Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
Synonyms: DNA-binding protein/plasminogen activator inhibitor 1 regulator, Helicase like transcription factor, Helicase-like transcription factor, HIP116, HIP116A, HLTF 1, HLTF, HLTF_HUMAN, HLTF1, p113, RING finger protein 80, RNF80, SMARC A3, SMARCA 3, SMARCA3, SNF2-like 3, SNF2L3, Sucrose nonfermenting protein 2 like 3, Sucrose nonfermenting protein 2-like 3, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3, ZBU 1, ZBU1. -
基因ID
- 6596
抗原
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