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HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 331-430) 抗体 (HRP)

The 兔 多克隆 anti-HERV-FRD Provirus Ancestral Env Polyprotein antibody is suitable to detect HERV-FRD Provirus Ancestral Env Polyprotein in samples from 人. It has been validated for WB, IHC (fro) 和 IHC (p).
产品编号 ABIN2175626
发货至: 中国
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Quick Overview for HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 331-430) 抗体 (HRP) (ABIN2175626)

抗原

See all HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) 抗体
HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

适用

  • 38
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人

宿主

  • 41
兔

克隆类型

  • 41
多克隆

标记

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HRP

应用范围

  • 37
  • 17
  • 13
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  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
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    AA 331-430

    原理

    ERVFRD-1 Polyclonal Antibody, HRP Conjugated

    交叉反应

    人

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Syncytin-2

    亚型

    IgG
  • 应用备注

    WB(1:300-5000),

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

    别名

    Syncytin 2

    背景

    Synonyms: envFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD_6p24.1 provirus ancestral Env polyprotein, ERVFRD-1, UNQ6191/PRO20218

    Background: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732). Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).

    基因ID

    405754

    UniProt

    P60508
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