HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 331-430) 抗体
(1 reference)Quick Overview for HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 331-430) 抗体 (ABIN2175615)
抗原
See all HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-430
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Syncytin-2
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亚型
- IgG
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anti-HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 16-250) antibody
Herv-frd 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 16-250) antibodyHerv-frd 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 33-315) antibodyHerv-frd 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 35-84) antibodyHerv-frd 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 79-107), (N-Term) antibodyHerv-frd 适用: 人 WB 宿主: 兔 Polyclonal RB32774 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 81, (2015) (PubMed).
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: "Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 81, (2015) (PubMed).
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- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
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别名
- Syncytin 2
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背景
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Synonyms: envFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD, Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD_6p24.1 provirus ancestral Env polyprotein, ERVFRD-1, UNQ6191/PRO20218
Background: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732). Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).
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基因ID
- 405754
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UniProt
- P60508
抗原
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