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GPR161 抗体 (AA 121-220)

This anti-GPR161 antibody is a 兔 多克隆 antibody detecting GPR161 in WB, ELISA, IF (cc), IF (p), IHC (p), ICC 和 IHC (fro). Suitable for 人.
产品编号 ABIN2174751
发货至: 中国

Quick Overview for GPR161 抗体 (AA 121-220) (ABIN2174751)

抗原

See all GPR161 抗体
GPR161 (G Protein-Coupled Receptor 161 (GPR161))

适用

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宿主

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克隆类型

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多克隆

标记

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This GPR161 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 121-220

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GPR161

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GPR161 (G Protein-Coupled Receptor 161 (GPR161))

    别名

    GPR161

    背景

    Synonyms: RE2, G-protein coupled receptor 161, G-protein coupled receptor RE2, GPR161

    Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

    基因ID

    23432

    UniProt

    Q8N6U8

    途径

    cAMP Metabolic Process
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