Human Papilloma Virus E7 (HPV E7) (Middle Region) 抗体 (Biotin)
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Quick Overview for Human Papilloma Virus E7 (HPV E7) (Middle Region) 抗体 (Biotin) (ABIN2173800)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody may also detect HPV35-E7
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交叉反应
- 人, Virus
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交叉反应 （详细）
- HPV16
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from middle of HPV16-E7
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亚型
- IgG
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anti-Human Papilloma Virus E7 (HPV E7) (Middle Region) antibody
HPV E7 适用: Human Papillomavirus 16 (HPV-16) WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Human Papilloma Virus E7 (HPV E7) antibodyHPV E7 适用: Human Papillomavirus 16 (HPV-16) WB, ELISA 宿主: 小鼠 Monoclonal 3D6F1 unconjugated
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应用备注
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WB 1:100-1000
IHC-P 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Human Papilloma Virus E7 (HPV E7)
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物质类
- Viral Protein
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背景
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Synonyms: Protein E7, E7
Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.
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基因ID
- 1489079
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UniProt
- P03129
抗原
-
