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CSRP2 抗体 (AA 101-200) (Biotin)

This anti-CSRP2 antibody is a Rabbit Polyclonal antibody detecting CSRP2 in WB, ELISA, IHC (p), IHC (fro). Suitable for Mouse, Rat, Chicken.
产品编号 ABIN2173631
发货至: 中国

Quick Overview for CSRP2 抗体 (AA 101-200) (Biotin) (ABIN2173631)

抗原

See all CSRP2 抗体
CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

适用

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  • 2
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小鼠, 大鼠, 小鸡

宿主

  • 57
  • 3
  • 1

克隆类型

  • 61
多克隆

标记

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This CSRP2 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 14
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    交叉反应

    小鸡, 小鼠, 大鼠

    预测反应

    Human,Dog,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DNM1L

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

    别名

    DLP1

    背景

    Synonyms: Dynamin-1-like protein, Dnm1p/Vps1p-like protein, DVLP, Dynamin family member proline-rich carboxyl-terminal domain less, Dymple, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, HdynIV, Dynamin-related protein 1, DNM1L, DLP1, DRP1

    Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.

    基因ID

    10059

    UniProt

    O00429
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