Cofilin 抗体 (pSer3)
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Quick Overview for Cofilin 抗体 (pSer3) (ABIN2173273)
抗原
See all Cofilin (CFL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer3
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原理
- Phospho-Cofilin (Ser3) Polyclonal Antibody
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特异性
- This phosphorylation site is homologous in the listed cross reactive species at the specified location.
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Cofilin around the phosphorylation site of Ser3
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亚型
- IgG
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应用备注
- WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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别名
- Cofilin
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背景
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Synonyms: CFL, cofilin, HEL-S-15, Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform, CFL1
Background: Binds to F-actin and exhibits pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.
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基因ID
- 1072
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UniProt
- P23528
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途径
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
抗原
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