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Claudin 23 抗体 (AA 25-81) (Cy3)

This Cy3-conjugated 兔 多克隆 anti-Claudin 23 antibody specifically detects Claudin 23 in IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN2173213
发货至: 中国
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Quick Overview for Claudin 23 抗体 (AA 25-81) (Cy3) (ABIN2173213)

抗原

See all Claudin 23 (CLDN23) 抗体
Claudin 23 (CLDN23)

适用

  • 34
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宿主

  • 34

克隆类型

  • 34
多克隆

标记

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This Claudin 23 antibody is conjugated to Cy3

应用范围

  • 14
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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
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    • 2
    • 1
    • 1
    AA 25-81

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Claudin 23

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Claudin 23 (CLDN23)

    别名

    Claudin 23

    背景

    Synonyms: 2310014B08Rik, Claudin23, CLDN 23, CLDN23, CLDNL.

    Background: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80 % sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor.

    途径

    Cell-Cell Junction Organization, Hepatitis C
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