(1 reference)-
- 抗原 See all CDK1 抗体
- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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抗原表位
- AA 201-297
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适用
- 人, 小鼠, 大鼠, 犬, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK1 antibody is conjugated to PE
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 犬, 人, 小鼠, 大鼠, 绵羊
- 预测反应
- Cow
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from mouse CDK1
- 亚型
- IgG
- Top Product
- Discover our top product CDK1 Primary Antibody
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anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 59-182) antibody
CDK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (pTyr15) antibodyCDK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 211-297) antibodyCDK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 1-297) antibodyCDK1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A4-1A9 unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 208-258) antibodyCDK1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) antibodyCDK1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 211-297) antibodyCDK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 8F1 unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 1-297) antibodyCDK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 66-297) antibodyCDK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 201-297) antibodyCDK1 适用: 人, 小鼠, 大鼠, 犬, 绵羊 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- FCM 1:20-100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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: "Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest." in: Tumour biology, Vol. 35, Issue 8, pp. 7561-8, (2014) (PubMed).
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: "Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest." in: Tumour biology, Vol. 35, Issue 8, pp. 7561-8, (2014) (PubMed).
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- 抗原
- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
- 别名
- CDK1 (CDK1 产品)
- 背景
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Synonyms: Cdc2, Cdc2a, p34, Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, Cdkn1
Background: The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
- 基因ID
- 12534
- UniProt
- P11440
- 途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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