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FAT4 抗体 (AA 4351-4450) (FITC)

This anti-FAT4 antibody is a 兔 多克隆 antibody detecting FAT4 in WB, IF (cc) 和 IF (p). Suitable for 小鼠 和 大鼠.
产品编号 ABIN2172813
发货至: 中国

Quick Overview for FAT4 抗体 (AA 4351-4450) (FITC) (ABIN2172813)

抗原

See all FAT4 抗体
FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))

适用

  • 18
  • 14
  • 14
小鼠, 大鼠

宿主

  • 29
  • 3

克隆类型

  • 29
  • 3
多克隆

标记

  • 9
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FAT4 antibody is conjugated to FITC

应用范围

  • 20
  • 12
  • 12
  • 8
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 5
    • 2
    • 1
    AA 4351-4450

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CDHF14

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))

    别名

    Cdhf14

    背景

    Synonyms: Cadherin family member 14, CDHF14, FAT tumor suppressor homolog 4, Fat-like cadherin protein FAT-J, FAT4, FAT4_HUMAN, FATJ, hFat4, Nbla00548, Protocadherin Fat 4.

    Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT4 (FAT tumor suppressor homolog 4), also known as FAT-J, CDHF14 or CDHR11, is a 4,981 amino acid single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins and localizes to the primary cilia of kidney. Widely expressed, FAT4 contains thirty-four cadherin domains, six EGF-like domains and two laminin G-like domains. FAT4 may function in the regulation of planar cell polarity.

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