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Carkd 抗体 (PE)

This anti-Carkd antibody (ABIN2172276) is a Rabbit Polyclonal antibody detecting Carkd in WB. Suitable for Human, Mouse, Rat.
产品编号 ABIN2172276
发货至: 中国

Quick Overview for Carkd 抗体 (PE) (ABIN2172276)

抗原

See all Carkd 抗体
Carkd (Carbohydrate Kinase Domain Containing (Carkd))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 19
多克隆

标记

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This Carkd antibody is conjugated to PE

应用范围

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Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CARKD

    亚型

    IgG
  • 应用备注

    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • 抗原

    Carkd (Carbohydrate Kinase Domain Containing (Carkd))

    别名

    CARKD

    背景

    Synonyms: Carbohydrate kinase domain containing, carbohydrate kinase domain-containing protein, FLJ10769, LP3298, NNRD_HUMAN.

    Background: CARKD is a 347 amino acid protein that belongs to the YjeF family and exists as three alternatively spliced isoforms. Containing one YjeF C-terminal domain, CARKD is encoded by a gene that maps to human chromosome 13q34. Chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

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