ANKRD11 抗体 (PE)
Quick Overview for ANKRD11 抗体 (PE) (ABIN2170178)
抗原
See all ANKRD11 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ANKRD11
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亚型
- IgG
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应用备注
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FCM: (1:20-100)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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- ANKRD11 (Ankyrin Repeat Domain 11 (ANKRD11))
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别名
- Ankrd11
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背景
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Synonyms: ANCO 1, ANCO1, Ankyrin repeat containing cofactor 1, Ankyrin repeat domain 11, Ankyrin repeat domain containing protein 11, LZ16, T13.
Background: Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 2224 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases, most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.
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基因ID
- 29123
抗原
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