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ALOX15 抗体 (AA 581-662)

Name: ALOX15 抗体 (AA 581-662)
SKU: ABIN2169710
Availability: OutOfStock

This anti-ALOX15 antibody is a 兔多克隆 antibody detecting ALOX15 in ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 大鼠和小鼠. This Primary Antibody has been cited in 1 publication.

(1 reference)

产品编号 ABIN2169710

发货至: 中国

Datasheet as PDF

Quick Overview for ALOX15 抗体 (AA 581-662) (ABIN2169710)

抗原

See all ALOX15 抗体

ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This ALOX15 antibody is un-conjugated

应用范围

ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product ALOX15 Primary Antibody

抗原表位
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12

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1

1

1
AA 581-662

交叉反应

人, 小鼠, 大鼠

预测反应

Cow,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human ALOX15/15 Lipoxygenase 1

亚型

IgG
anti-Arachidonate 15-Lipoxygenase (ALOX15) antibody
ALOX15 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G8 unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibody
ALOX15 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 2-337) antibody
ALOX15 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 170-312) antibody
ALOX15 适用: 人 WB 宿主: 小鼠 Monoclonal 6# unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibody
ALOX15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (Internal Region) antibody
Verified ALOX15 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 610-643), (C-Term) antibody
ALOX15 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17156 unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-225) antibody
ALOX15 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-663) antibody
ALOX15 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated

anti-Arachidonate 15-Lipoxygenase (ALOX15) antibody
ALOX15 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Francos-Quijorna, Amo-Aparicio, Martinez-Muriana, López-Vales: "IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury." in: Glia, Vol. 64, Issue 12, pp. 2079-2092, (2016) (PubMed).
抗原

ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

别名

15 Lipoxygenase 1

背景

Synonyms: 12-LOX, 15LOX-1, 15-LOX-1, Arachidonate 15-lipoxygenase, 15-LOX, 12/15-lipoxygenase, Arachidonate 12-lipoxygenase, leukocyte-type, Arachidonate omega-6 lipoxygenase, ALOX15, LOG15
Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

基因ID

246

UniProt

P16050

途径

Regulation of Actin Filament Polymerization