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CD8 alpha 抗体

This 大鼠 单克隆 antibody specifically detects CD8 alpha in FACS, IHC 和 IP. It exhibits reactivity toward 小鼠.
产品编号 ABIN933904
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD8 alpha 抗体 (ABIN933904)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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小鼠

宿主

  • 238
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大鼠

克隆类型

  • 440
  • 109
  • 3
单克隆

标记

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This CD8 alpha antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

53-6-7
  • 免疫原

    CD8 a antibody was raised in rat using murine thymus or spleen as the immunogen.

    亚型

    IgG2a
  • 应用备注

    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Supplied as a liquid in 100 mM BBS, pH 8.2.

    储存条件

    4 °C

    储存方法

    Store at 4 °C.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    CD8a (Cluster of Differentiation 8a), is a human gene. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified. Synonyms: Monoclonal CD8a antibody, Anti-CD8a antibody, Ly2 antibody.

    途径

    TCR Signaling
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