Synaptophysin 抗体
Quick Overview for Synaptophysin 抗体 (ABIN211569)
抗原
See all Synaptophysin (SYP) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human synaptophysin, also known as Major synaptic vesicle protein p38. Synaptophysin is a 313 amino acid synaptic vesicle associated protein of ~38kD containing a single domain. Synaptophysin expression is ubiquitous in synaptic vesicle membranes where it is the most abundant protein and is involved in the regulation of endocytosis Loss and atypical expression of synaptophysin is noted in conditions such as Huntingdon's disease and Alzheimer's disease. Mutations in the synaptophysin gene have been identified and lead to a condition, Mental retardation, X-linked 96. Has been used for the detection of synaptophysin by immunofluorescence, immunohistochemistry and western blotting on murine, marmoset, rat, lapine and human tissues.
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纯化方法
- Gel filtration
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免疫原
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Crude human synaptic immunoprecipitate.
Type of Immunogen: Protein extract -
亚型
- IgM
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应用备注
- Approved: ELISA, IHC, IHC-P (1:25), WB (1:500)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.2, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Synaptophysin (SYP)
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别名
- SYP / Synaptophysin
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背景
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Name/Gene ID: SYP
Synonyms: SYP, MRX, Synaptophysin, MRXSYP -
基因ID
- 6855
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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