CD80 抗体
Quick Overview for CD80 抗体 (ABIN211324)
抗原
See all CD80 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts with the murine CD80 (B7-1) molecule. This member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages, and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours
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纯化方法
- Purified
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免疫原
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Type of Immunogen: Native protein -
亚型
- IgG2a
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应用备注
- Approved: Flo (0.25 μg/10 x106)
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说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
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- CD80
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别名
- CD80 / B7
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背景
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Name/Gene ID: CD80
Synonyms: CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 Molecule, CTLA-4 counter-receptor B7.1 -
基因ID
- 941
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UniProt
- P33681
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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