alpha Fetoprotein 抗体
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北京 101111
Quick Overview for alpha Fetoprotein 抗体 (ABIN210027)
抗原
See all alpha Fetoprotein (AFP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a 68kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults. Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome. 4520-5306 does not cross-react with human albumin and other human serum proteins.
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纯化方法
- Ion exchange chromatography
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免疫原
- Native, from fetal cord.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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别名
- AFP / alpha Fetoprotein
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背景
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Name/Gene ID: AFP
Synonyms: AFP, Alpha-1-fetoprotein, Alpha-fetoprotein, HPAFP, Alpha-fetoglobulin, FETA -
基因ID
- 174
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途径
- C21-Steroid Hormone Metabolic Process
抗原
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