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PDCD1LG2 抗体 (FITC)

This anti-PDCD1LG2 antibody is a 大鼠 单克隆 antibody detecting PDCD1LG2 in FACS, IHC, IP 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN207224
发货至: 中国

Quick Overview for PDCD1LG2 抗体 (FITC) (ABIN207224)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

适用

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小鼠

宿主

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  • 13
  • 1
大鼠

克隆类型

  • 80
  • 45
  • 2
单克隆

标记

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This PDCD1LG2 antibody is conjugated to FITC

应用范围

  • 72
  • 65
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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD279). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to its receptor. XXX recommend the use of MCA2465EL for functional studies.

    纯化方法

    Protein G purified

    免疫原

    B7-DC transfected RAW264.7 cells.

    亚型

    IgG2a
  • 应用备注

    Approved: Flo (1:1 - 1:5), IHC, IHC-Fr, IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    PDCD1LG2 / CD273 / PD-L2

    背景

    Name/Gene ID: PDCD1LG2

    Synonyms: PDCD1LG2, B7 dendritic cell molecule, B7-DC, B7DC, BA574F11.2, CD273, Btdc, CD273 antigen, PD-L2, PDCD1 ligand 2, PD-1-ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, PD-1 ligand 2, PDCD1L2, PDL2

    基因ID

    80380

    UniProt

    Q9BQ51
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