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SOCS3 抗体

This 小鼠 单克隆 antibody specifically detects SOCS3 in WB 和 Inhibition. It exhibits reactivity toward 人.
产品编号 ABIN207073
发货至: 中国
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Quick Overview for SOCS3 抗体 (ABIN207073)

抗原

See all SOCS3 抗体
SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SOCS3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Blocking Antibody (Inhibition)

克隆位点

SO1
  • 特异性

    The cytokine signaling is known to be regulated by a negative feedback regulator called suppressor of cytokine signaling (SOCS) inhibitors family. Members of the SOCS family have been identified due to their marked homology on the SH2 domain and a unique conserved motif referred to as the SOCS box. Expression of SOCS3 is transiently induced in a variety of immune and inflammatory situations by a wide variety of cytokines. SOCS3 is also involved in growth hormone function, leptin and insulin signaling. SOCS3 inhibits Janus kinase (JAK) tyrosine kinase activity

    纯化方法

    Protein A purified

    免疫原

    Full-length SOCS3 protein.

    Type of Immunogen: Recombinant protein

    亚型

    IgG2b
  • 应用备注

    Approved: Inhb, WB

    Usage: Western Blotting: Positive control - HeLa human cervix carcinoma cell line. Sample preparation: Resuspend approx. 50 mil. cells in 1 mL cold Lysis buffer (1 % laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl  pH 8.2, 50 mM NaF including Protease inhibitor Cock

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 15 mM sodium azide, approx,  pH 7.4.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    avoid freeze thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
  • 抗原

    SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

    别名

    SOCS3

    背景

    Name/Gene ID: SOCS3

    Synonyms: SOCS3, Cish3, Cytokine-induced SH2 protein 3, CIS-3, CIS3, SSI-3, STAT-induced STAT inhibitor 3, SSI3, ATOD4, SOCS-3

    基因ID

    9021

    UniProt

    O14543

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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