SOCS3 抗体
Quick Overview for SOCS3 抗体 (ABIN207073)
抗原
See all SOCS3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The cytokine signaling is known to be regulated by a negative feedback regulator called suppressor of cytokine signaling (SOCS) inhibitors family. Members of the SOCS family have been identified due to their marked homology on the SH2 domain and a unique conserved motif referred to as the SOCS box. Expression of SOCS3 is transiently induced in a variety of immune and inflammatory situations by a wide variety of cytokines. SOCS3 is also involved in growth hormone function, leptin and insulin signaling. SOCS3 inhibits Janus kinase (JAK) tyrosine kinase activity
-
纯化方法
- Protein A purified
-
免疫原
-
Full-length SOCS3 protein.
Type of Immunogen: Recombinant protein -
亚型
- IgG2b
-
-
-
-
应用备注
-
Approved: Inhb, WB
Usage: Western Blotting: Positive control - HeLa human cervix carcinoma cell line. Sample preparation: Resuspend approx. 50 mil. cells in 1 mL cold Lysis buffer (1 % laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl pH 8.2, 50 mM NaF including Protease inhibitor Cock -
说明
-
Target Species of Antibody: Human
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- PBS, 15 mM sodium azide, approx, pH 7.4.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- avoid freeze thaw cycles.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
-
-
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
-
别名
- SOCS3
-
背景
-
Name/Gene ID: SOCS3
Synonyms: SOCS3, Cish3, Cytokine-induced SH2 protein 3, CIS-3, CIS3, SSI-3, STAT-induced STAT inhibitor 3, SSI3, ATOD4, SOCS-3 -
基因ID
- 9021
-
UniProt
- O14543
-
途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
抗原
-