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ITGA6 抗体 (PE)

ITGA6 适用: 人, 小鼠, 犬, Pig, 绵羊, Cynomolgus FACS, IHC, IP, IHC (fro) 宿主: 大鼠 Monoclonal PE
产品编号 ABIN206771
发货至: 中国
  • 抗原 See all ITGA6 抗体
    ITGA6 (Integrin, alpha 6 (ITGA6))
    适用
    • 114
    • 50
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    • 6
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    • 5
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    人, 小鼠, 犬, Pig, 绵羊, Cynomolgus
    宿主
    • 70
    • 36
    • 15
    • 2
    大鼠
    克隆类型
    • 65
    • 56
    单克隆
    标记
    • 66
    • 11
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    • 5
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    This ITGA6 antibody is conjugated to PE
    应用范围
    • 78
    • 47
    • 44
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    • 22
    • 18
    • 13
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    • 11
    • 10
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. XXX recommend the use of MCA699XZ for this purpose.
    纯化方法
    Protein G purified
    免疫原
    BALB/c mouse mammary tumor cells.

    Type of Immunogen: Cells
    亚型
    IgG2a
    Top Product
    Discover our top product ITGA6 Primary Antibody
  • 应用备注
    Approved: Flo (1:1 - 1:5), IHC, IHC-Fr, IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL. Method sheets are available on request.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Distilled Water.
    浓度
    Lot specific
    缓冲液
    Lyophilized powder from PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 4°C. Do not freeze.
  • 抗原
    ITGA6 (Integrin, alpha 6 (ITGA6))
    别名
    ITGA6/Integrin Alpha 6/CD49f (ITGA6 产品)
    别名
    CD49f antibody, ITGA6B antibody, VLA-6 antibody, 5033401O05Rik antibody, AI115430 antibody, Cd49f antibody, ITGA6 antibody, inta6 antibody, im:6897425 antibody, itga6 antibody, si:dkey-32o22.1 antibody, wu:fb80g02 antibody, LOC100221694 antibody, si:dkey-18j14.1 antibody, wu:fl20e08 antibody, zgc:113088 antibody, integrin subunit alpha 6 antibody, integrin alpha 6 antibody, integrin subunit alpha 6 L homeolog antibody, integrin, alpha 6a antibody, integrin, alpha 6b antibody, ITGA6 antibody, Itga6 antibody, itga6.L antibody, itga6a antibody, itga6b antibody
    背景
    Name/Gene ID: ITGA6
    Family: Integrin

    Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B
    基因ID
    3655
    UniProt
    P23229
    途径
    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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