ITGA6 抗体 (PE)
-
- 抗原 See all ITGA6 抗体
- ITGA6 (Integrin, alpha 6 (ITGA6))
-
适用
- 人, 小鼠, 犬, Pig, 绵羊, Cynomolgus
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This ITGA6 antibody is conjugated to PE
-
应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
- 特异性
- Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. XXX recommend the use of MCA699XZ for this purpose.
- 纯化方法
- Protein G purified
- 免疫原
-
BALB/c mouse mammary tumor cells.
Type of Immunogen: Cells - 亚型
- IgG2a
- Top Product
- Discover our top product ITGA6 Primary Antibody
-
-
- 应用备注
-
Approved: Flo (1:1 - 1:5), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL. Method sheets are available on request. - 说明
-
Target Species of Antibody: Human
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Distilled Water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder from PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C. Do not freeze.
-
- 抗原
- ITGA6 (Integrin, alpha 6 (ITGA6))
- 别名
- ITGA6/Integrin Alpha 6/CD49f (ITGA6 产品)
- 背景
-
Name/Gene ID: ITGA6
Family: Integrin
Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B - 基因ID
- 3655
- UniProt
- P23229
- 途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
-