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ITGA6 抗体 (PE)

This anti-ITGA6 antibody is a 大鼠 单克隆 antibody detecting ITGA6 in FACS, IHC, IP 和 IHC (fro). Suitable for 人, 小鼠, 犬, Pig, 绵羊 和 Cynomolgus.
产品编号 ABIN206771
发货至: 中国

Quick Overview for ITGA6 抗体 (PE) (ABIN206771)

抗原

See all ITGA6 抗体
ITGA6 (Integrin, alpha 6 (ITGA6))

适用

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人, 小鼠, 犬, Pig, 绵羊, Cynomolgus

宿主

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大鼠

克隆类型

  • 75
  • 64
单克隆

标记

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This ITGA6 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. XXX recommend the use of MCA699XZ for this purpose.

    纯化方法

    Protein G purified

    免疫原

    BALB/c mouse mammary tumor cells.

    Type of Immunogen: Cells

    亚型

    IgG2a
  • 应用备注

    Approved: Flo (1:1 - 1:5), IHC, IHC-Fr, IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL. Method sheets are available on request.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Distilled Water.

    浓度

    Lot specific

    缓冲液

    Lyophilized powder from PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 4°C. Do not freeze.
  • 抗原

    ITGA6 (Integrin, alpha 6 (ITGA6))

    别名

    ITGA6/Integrin Alpha 6/CD49f

    背景

    Name/Gene ID: ITGA6
    Family: Integrin

    Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B

    基因ID

    3655

    UniProt

    P23229

    途径

    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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