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ITGA6 抗体

This 大鼠 单克隆 antibody specifically detects ITGA6 in FACS, IHC, IP 和 IHC (fro). It exhibits reactivity toward 人, 小鼠, 犬, Pig, 绵羊 和 Cynomolgus.
产品编号 ABIN206770
发货至: 中国
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Quick Overview for ITGA6 抗体 (ABIN206770)

抗原

See all ITGA6 抗体
ITGA6 (Integrin, alpha 6 (ITGA6))

适用

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人, 小鼠, 犬, Pig, 绵羊, Cynomolgus

宿主

  • 90
  • 44
  • 17
  • 2
大鼠

克隆类型

  • 78
  • 73
单克隆

标记

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This ITGA6 antibody is un-conjugated

应用范围

  • 86
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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Recognizes the CD49f-antigen, (VLA-6 alpha-chain). CD49f can form distinct complexes with either the CD29-antigen (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology this Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytiotrophoblasts. Platelet VLA-6 functions as a laminin receptor. This clone has been reported to inhibit platelet adhesion to laminin.

    纯化方法

    Protein G purified

    免疫原

    BALB/c mouse mammary tumor cells.

    Type of Immunogen: Cells

    亚型

    IgG2a
  • 应用备注

    Approved: Flo, IHC, IHC-Fr, IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL. Method sheets are available on request.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    ITGA6 (Integrin, alpha 6 (ITGA6))

    别名

    ITGA6/Integrin alpha 6/CD49f

    背景

    Name/Gene ID: ITGA6
    Family: Integrin

    Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B

    基因ID

    3655

    途径

    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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