ITGA6 抗体
Quick Overview for ITGA6 抗体 (ABIN206770)
抗原
See all ITGA6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes the CD49f-antigen, (VLA-6 alpha-chain). CD49f can form distinct complexes with either the CD29-antigen (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology this Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytiotrophoblasts. Platelet VLA-6 functions as a laminin receptor. This clone has been reported to inhibit platelet adhesion to laminin.
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纯化方法
- Protein G purified
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免疫原
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BALB/c mouse mammary tumor cells.
Type of Immunogen: Cells -
亚型
- IgG2a
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应用备注
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Approved: Flo, IHC, IHC-Fr, IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL. Method sheets are available on request. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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别名
- ITGA6/Integrin alpha 6/CD49f
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背景
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Name/Gene ID: ITGA6
Family: Integrin
Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B -
基因ID
- 3655
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途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
抗原
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