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Complement C4d 抗体

C4d 适用: 人 ELISA, IHC, IHC (fro), FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN206675
发货至: 中国
  • 抗原 See all Complement C4d (C4d) products
    Complement C4d (C4d) (Complement Component C4d (C4d))
    适用
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    宿主
    • 27
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    小鼠
    克隆类型
    • 28
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    单克隆
    标记
    • 17
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    This Complement C4d antibody is un-conjugated
    应用范围
    • 21
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    ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    特异性
    Recognizes a neoantigen on the secreted protein complement component 4d (C4d). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosus.
    纯化方法
    Protein A purified
    免疫原
    Purified human C4d.
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Borate buffered saline,  pH 8.2 - 8.4, 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    Complement C4d (C4d) (Complement Component C4d (C4d))
    别名
    Complement C4d (C4d 产品)
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