Complement C4d 抗体
Quick Overview for Complement C4d 抗体 (ABIN206675)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes a neoantigen on the secreted protein complement component 4d (C4d). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosus.
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纯化方法
- Protein A purified
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免疫原
- Purified human C4d.
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亚型
- IgG1
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anti-Complement Component C4d (C4d) (Internal Region) antibody
C4d 适用: 人 IHC (p) 宿主: 兔 Monoclonal A24-T unconjugated
anti-Complement Component C4d (C4d) antibodyC4d 适用: 人 IF, ELISA, Coat, IHC (f) 宿主: 小鼠 Monoclonal C4D204 unconjugated
anti-Complement Component C4d (C4d) (AA 958-1335) antibodyC4d 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4d (C4d) (AA 958-1335) antibodyC4d 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Complement Component C4d (C4d) (AA 1241-1256) antibodyC4d 适用: 人 IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C4d (C4d) antibodyC4d 适用: 人 IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal C4D204 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Borate buffered saline, pH 8.2 - 8.4, 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Complement C4d (C4d) (Complement Component C4d (C4d))
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别名
- Complement C4d
抗原
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