Complement C8 抗体
C8
适用: 人
FACS, WB, ELISA, IHC, IHC (fro)
宿主: 小鼠
Monoclonal
056B-373
unconjugated
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- 抗原 See all Complement C8 (C8) products
- Complement C8 (C8)
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Complement C8 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Recognizes complement component 8 (C8), a 151 kD member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 Molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.
- 纯化方法
- Protein A purified
- 免疫原
- Purified human C8.
- 克隆位点
- 056B-373
- 亚型
- IgG1
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Borate buffered saline, pH 8.2 - 8.4, 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- Complement C8 (C8)
- 别名
- Complement C8 (C8 产品)
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