Complement C3d 抗体
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- 抗原 See all Complement C3d (C3d) products
- Complement C3d (C3d) (Complement Fragment 3d (C3d))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Complement C3d antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
- 特异性
- Specific for human complement component 3d (C3d), a 33kD polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
- 纯化方法
- Protein A purified
- 免疫原
- Purified C3d from human plasma.
- 亚型
- IgG1
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- 应用备注
- Approved: ELISA, Flo, IHC, IHC-Fr, WB (1:5000)
- 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Borate buffered saline, 0.1 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- avoid freeze thaw cycles. Store undiluted.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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