CCL5 抗体
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北京 101111
Quick Overview for CCL5 抗体 (ABIN205820)
抗原
See all CCL5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human RANTES (regulated upon activation, normal T cell expressed and secreted), otherwise known as CCL5, a 68 amino acid CC- chemokine involved in T cell activation and cell recruitment, expressed by cytotoxic (CD8+) T cells (CTLs), macrophages, keratinocytes and endothelial cells. RANTES acts as a chemoattractant for monocytes, CD4+/CD45RO+ memory T cells, basophils and eosinophils, thorough binding to chemokine (C-C motif) receptor 1 (CCR1), CCR3 and CCR5. Both CCR3 and CCR5 are known co-receptors for the entry of HIV viruses into target cells and the binding of RANTES to CCR3 on CTLs has been shown to enhance HIV-1-specific cytotoxicity, whilst binding to CCR5 inhibits membrane fusion and hence HIV entry.
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纯化方法
- Purified
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免疫原
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Recombinant human RANTES.
Type of Immunogen: Recombinant protein -
亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibody
CCL5 适用: 犬 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 62-91) antibodyCCL5 适用: 人, 小鼠, 豚鼠, Pig ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) antibodyCCL5 适用: 人 WB, ELISA, Func, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) antibody (Biotin)CCL5 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) antibodyCCL5 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: 猕猴 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 5 (CCL5) (AA 24-91) antibodyCCL5 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Approved: ELISA (0.5 - 2 μg/mL), Func (5 - 7 μg/mL), WB (0.1 - 0.2 μg/mL)
Usage: ELISA: May be used in an indirect ELISA or as a capture reagent in a sandwich ELISA. Western Blot: May be used in either reducing or non-reducing conditions. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.
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浓度
- Lot specific
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缓冲液
- Lyophilized, PBS, pH 7.4.
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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别名
- CCL5 / RANTES
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背景
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Name/Gene ID: CCL5
Family: Intercrine
Synonyms: CCL5, Chemokine (C-C motif) ligand 5, D17S136E, EoCP, T-cell specific protein p288, SCYA5, SISd, T cell-specific protein P228, Beta-chemokine RANTES, C-C motif chemokine 5, RANTES, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES, TCP228 -
基因ID
- 6352
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
抗原
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