IGFBP7 抗体
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北京 101111
Quick Overview for IGFBP7 抗体 (ABIN205804)
抗原
See all IGFBP7 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human IGFBP-7 (insulin-like growth factor binding protein-7), also known as mac25, a 256 amino acid secreted protein and member of a growing family of IGFBPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II. IGFBP-7 is widely expressed throughout normal tissues, but is also expressed in many tumor types at an increased or reduced level, and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation, by its possible affects on the actions of parathyroid hormone (PTH) and cortisol.
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纯化方法
- Purified
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免疫原
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Recombinant human IGFBP-7.
Type of Immunogen: Recombinant protein -
亚型
- IgG
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应用备注
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Approved: ELISA (0.5 - 2 μg/mL), WB (0.1 - 0.2 μg/mL)
Usage: ELISA: LS-C42599 may be used in an indirect ELISA or as a capture reagent in sandwich ELISA. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.
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浓度
- Lot specific
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缓冲液
- Lyophilized, PBS, pH 7.2.
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- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
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别名
- IGFBP7 / TAF
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背景
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Name/Gene ID: IGFBP7
Synonyms: IGFBP7, AGM, FSTL2, IGFBP-7v, IGFBP-rP1, IBP-7, Angiomodulin, RAMSVPS, MAC25 protein, PSF, TAF, Tumor-derived adhesion factor, IGF-binding protein 7, IGFBP-7, IGFBPRP1, MAC25, PGI2-stimulating factor -
基因ID
- 3490
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途径
- Growth Factor Binding
抗原
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