Rabies Virus Nucleoprotein (RABV N) 抗体
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北京 101111
Quick Overview for Rabies Virus Nucleoprotein (RABV N) 抗体 (ABIN1993849)
抗原
适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Caprylic Acid Ammonium Sulfate Precipitation
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免疫原
- Recombinant Rabies virus Nucleoprotein protein
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亚型
- IgG
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应用备注
- Optimal working concentration should be determinde by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4
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储存液
- ProClin
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注意事项
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze.
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储存条件
- -20 °C/-80 °C
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储存方法
- Upon delivery aliquot and store at -20 °C or -80 °C.
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- Rabies Virus Nucleoprotein (RABV N)
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别名
- Rabies Virus Nucleoprotein
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物质类
- Influenza Protein
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背景
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Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it\'s own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
Synonyms: NP, Nucleocapsid protein, Protein N, N -
UniProt
- P15197
抗原
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