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TIMP1 抗体 (AA 24-217) (FITC)

This anti-TIMP1 antibody is a 兔 多克隆 antibody detecting TIMP1 in WB 和 ELISA. Suitable for 大鼠.
产品编号 ABIN1993121
发货至: 中国

Quick Overview for TIMP1 抗体 (AA 24-217) (FITC) (ABIN1993121)

抗原

See all TIMP1 抗体
TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This TIMP1 antibody is conjugated to FITC

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 24-217

    交叉反应

    大鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA)

    亚型

    IgG
  • 应用备注

    Optimal working concentration should be determinde by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

    别名

    Timp1

    背景

    Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells, procathepsin L is required for maximal activity.

    Aliases: Timp1 antibody, Timp-1 antibody, Metalloproteinase inhibitor 1 antibody, Tissue inhibitor of metalloproteinases 1 antibody, TIMP-1 antibody

    UniProt

    P30120
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