IL12B 抗体 (AA 23-327) (FITC)
Quick Overview for IL12B 抗体 (AA 23-327) (FITC) (ABIN1992863)
抗原
See all IL12B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 23-327
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交叉反应
 - 绵羊
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纯化方法
 - >95%, Protein G purified
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免疫原
 - Recombinant Sheep Interleukin-12 subunit beta protein (23-327AA)
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亚型
 - IgG
 
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应用备注
 - Optimal working concentration should be determinde by the investigator.
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
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                        Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 
                                            
储存液
 - ProClin
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注意事项
 - This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze.
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储存条件
 - -20 °C,-80 °C
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储存方法
 - Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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- IL12B (Interleukin 12 beta (IL12B))
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别名
 - IL12B
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背景
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Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC By similarity.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis By similarity.
Aliases: IL12B antibody, Interleukin-12 subunit beta antibody, IL-12B antibody, Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody, CLMF p40 antibody, IL-12 subunit p40 antibody
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UniProt
 - P68220
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途径
 - JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
 
抗原
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