ADAM15 抗体 (AA 207-452) (FITC)
Quick Overview for ADAM15 抗体 (AA 207-452) (FITC) (ABIN1992070)
抗原
See all ADAM15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 207-452
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)
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亚型
- IgG
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应用备注
- Optimal working concentration should be determinde by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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别名
- ADAM15
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背景
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Background: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Aliases: A disintegrin and metalloproteinase domain 15 (metargidin) antibody, A disintegrin and metalloproteinase domain 15 antibody, ADA15_HUMAN antibody, ADAM 15 antibody, ADAM metallopeptidase domain 15 antibody, Adam15 antibody, and cysteine-rich protein 15 antibody, Disintegrin and metalloproteinase domain-containing protein 15 antibody, disintegrin-like antibody, EC 3.4.24. antibody, MDC 15 antibody, MDC-15 antibody, MDC15 antibody, Metalloprotease RGD disintegrin protein antibody, Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody, Metalloproteinase-like antibody, Metargidin antibody
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UniProt
- Q13444
抗原
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