Endothelin 1 抗体 (C-Term)
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Quick Overview for Endothelin 1 抗体 (C-Term) (ABIN198265)
抗原
See all Endothelin 1 (EDN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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特异性
- Recognizes human endothelin 1 (ET-1). Endothelin-1 in it's precursor form is a 212 amino acid protein with a 17 aa signal peptide, an N-terminal pro-peptide region and a C-terminal pro-peptide region flanking the endothelin peptides, big endothelin-1 (38aa), the precursor of the smaller endothelin peptide which is cleaved by endothelin converting enzyme to produce the active endothelin-1 (21aa) peptide and a c-terminal fragment. Endothelin-1 is a potent vasoconstrictor with a molecular weight of approximately 25 kD. Shows less than 10 % reactivity with endothelin 3. Plasma levels of both endothelin-1 and big endothelin-1 are useful as predictors for survival of patients with congestive heart failure. However, the half life of the endothlin1 peptide in human plasma is very short (c1.0 mins) and measurement of big-endothelin-1 may be a more reliable measure of the endothelin secretory pathway activity.
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纯化方法
- Protein A purified
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免疫原
- C-terminal fragment of human endothelin 1.
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亚型
- IgG1
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anti-Endothelin 1 (EDN1) (AA 33-202) antibody
EDN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 1 (EDN1) (AA 53-90) antibodyEDN1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Endothelin 1 (EDN1) (AA 18-212) antibodyEDN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 1 (EDN1) (AA 113-212) antibodyEDN1 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 3D6 unconjugated
anti-Endothelin 1 (EDN1) (AA 53-90) antibodyEDN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 1 (EDN1) (AA 118-146), (Middle Region) antibodyEDN1 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 1 (EDN1) (AA 53-73) antibodyEDN1 适用: 人, 大鼠, Pig, 小鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Endothelin 1 (EDN1) antibodyEDN1 适用: 人, 大鼠 WB, IF (p), IHC (p) 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Endothelin 1 (EDN1) (AA 53-203) antibodyEDN1 适用: Pig WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 5# unconjugated
anti-Endothelin 1 (EDN1) (C-Term) antibodyEDN1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.2, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Short term: -20°C
Long term: -20°C.
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- Endothelin 1 (EDN1)
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别名
- EDN1 / Endothelin 1
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背景
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Name/Gene ID: EDN1
Family: Hormone
Synonyms: EDN1, Endothelin 1, Endothelin-1, ET1, Preproendothelin-1, PPET1, HDLCQ7 -
基因ID
- 1906
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UniProt
- P05305
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途径
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
抗原
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