CD160 抗体 (PE)
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北京 101111
Quick Overview for CD160 抗体 (PE) (ABIN1981901)
抗原
See all CD160 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD160 PE
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交叉反应 （详细）
- Human
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产品特性
- The mouse monoclonal antibody BY55 recognizes an extracellular epitope of CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. The antibody detects both GPI-anchored and transmembrane form of CD160.
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human NK cell line YT2C2
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亚型
- IgM, kappa
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anti-CD160 (CD160) (AA 81-159) antibody
CD160 适用: 人, 大鼠 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) antibodyCD160 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal BY55 unconjugated
anti-CD160 (CD160) antibody (APC)CD160 适用: 人 FACS 宿主: 小鼠 Monoclonal BY55 APC
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD160 (CD160) (AA 33-171) antibodyCD160 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (Internal Region) antibodyCD160 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze,Protect from prolonged exposure to light
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
: "BY55/CD160 cannot be considered a cytotoxic marker in cytomegalovirus-specific human CD8(+) T cells." in: Clinical and experimental immunology, Vol. 149, Issue 1, pp. 87-96, (2007) (PubMed).
: "Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 6, pp. 2780-90, (1998) (PubMed).
: "BY55 monoclonal antibody delineates within human cord blood and bone marrow lymphocytes distinct cell subsets mediating cytotoxic activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 19, pp. 9136-40, (1994) (PubMed).
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: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
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- CD160
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别名
- CD160
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背景
- CD160 Molecule,CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.,NK1, NK28
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基因ID
- 11126
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UniProt
- O95971
抗原
-
