CD160 抗体 (PE)
(4 references)Quick Overview for CD160 抗体 (PE) (ABIN1981901)
抗原
See all CD160 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD160 PE
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特异性
- The mouse monoclonal antibody BY55 recognizes an extracellular epitope of CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. The antibody detects both GPI-anchored and transmembrane form of CD160.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human NK cell line YT2C2
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亚型
- IgM kappa
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anti-CD160 (CD160) (AA 81-159) antibody
CD160 适用: 人, 大鼠 WB, FACS, ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) antibodyCD160 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal BY55 unconjugated
anti-CD160 (CD160) antibody (APC)CD160 适用: 人 FACS 宿主: 小鼠 Monoclonal BY55 APC
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (Internal Region) antibodyCD160 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD160 (CD160) (AA 33-171) antibodyCD160 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-CD160 (CD160) (AA 27-136) antibodyCD160 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
: "BY55/CD160 cannot be considered a cytotoxic marker in cytomegalovirus-specific human CD8(+) T cells." in: Clinical and experimental immunology, Vol. 149, Issue 1, pp. 87-96, (2007) (PubMed).
: "Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 6, pp. 2780-90, (1998) (PubMed).
: "BY55 monoclonal antibody delineates within human cord blood and bone marrow lymphocytes distinct cell subsets mediating cytotoxic activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 19, pp. 9136-40, (1994) (PubMed).
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: "Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 63-71, (2008) (PubMed).
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- CD160
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别名
- CD160
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背景
- CD160 Molecule,CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.,NK1, NK28
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基因ID
- 11126
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UniProt
- O95971
抗原
-
