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CD101 抗体 (PE)

This 小鼠 单克隆 antibody specifically detects CD101 in FACS. It exhibits reactivity toward 人. It has been mentioned in 2+ publications
产品编号 ABIN1981894
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD101 抗体 (PE) (ABIN1981894)

抗原

See all CD101 抗体
CD101

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD101 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

BB27
  • 原理

    Anti-Hu CD101 PE

    交叉反应 (详细)

    Human

    产品特性

    The mouse monoclonal antibody BB27 recognizes an extracellular epitope of CD101, a 140 kDa disulfide-bonded homodimeric protein expressed on activated T cells, and some other cell types, such as granulocytes and cells of the monocyte/macropgage lineage.

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human thymic clone B12

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze,Protect from prolonged exposure to light

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Grassi, Dezutter-Dambuyant, McIlroy, Jacquet, Yoneda, Imamura, Boumsell, Schmitt, Autran, Debré, Hosmalin: "Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules." in: Journal of leukocyte biology, Vol. 64, Issue 4, pp. 484-93, (1998) (PubMed).

    Bagot, Martinel, Charue, Weill, Boulland, Wechsler, Freeman, Bensussan, Boumsell: "CD101 is expressed by skin dendritic cells. Role in T-lymphocyte activation." in: Tissue antigens, Vol. 50, Issue 5, pp. 439-48, (1998) (PubMed).

  • 抗原

    CD101

    别名

    CD101

    背景

    CD101 Molecule,CD101 is a type I transmembrane glycoprotein, which forms disulfide-linked homodimers. It is expressed on activated T cells, as well as on granulocytes, monocytes, dendritic cells or mucosal T cells. It plays a major role in the activation of T cells by skin dendritic cells. Function of CD101 has not been fully elucidated, but in mice its knock-out results in liver autoimmune disease induced by Novosphingobium aromaticivorans.,IGSF2, V7, EWI-101

    基因ID

    9398

    UniProt

    Q93033
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